Mary Spilker is a Bioengineer within the Computational Biology and Biostatistics group at General Electric's Global Research Center. She received her BS degree in Biomechanical Engineering from Marquette University and her PhD in Bioengineering from the University of Washington. Her current interests include quantification of imaging datasets, the application of modeling and simulations methods to improve the development of new imaging agents, and the use of preclinical and clinical imaging in pharmaceutical development. Her doctoral research was focused on the application of Bayesian statistics to parametric image analysis of dynamic contrast-enhanced MRI data. Through this work she was able to interact with leading researchers at the University of Washington and the University of California, San Francisco. Following her doctoral studies, she was a post-doctoral researcher within the Nuclear Medicine department at the Klinikum rechts der Isar in Munich Germany. During this time, she used kinetic modeling methods to quantify neurology imaging studies. After her post-doctoral position, Dr. Spilker joined General Electric's Global Research Center and has focused on the use of modeling and simulation methods to improve the development of new imaging agents.